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. 2016 Nov 25;9:257. doi: 10.1186/s13068-016-0673-0

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Simplified metabolic pathway for CoA biosynthesis in Saccharomyces cerevisiae. Shown are the relevant steps in yeast’s metabolism for endogenous synthesis of free CoA. The precursor pantothenate can be taken from medium via transporter Fen2 or can be synthesized endogenously from amino acids