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. 2016 Nov 25;35:180. doi: 10.1186/s13046-016-0454-4

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The Hi-C data showing that there are intensive chromosome interactions around chromosome regions within 3225000 bp of 6 HPV16 integrating sites corresponding to 3 chromosome translocation events (a-f) at the resolution of 25,000 bp. Hi-C data of GM12878 cell line was downloaded from the Interactive Hi-C Data Browser (http://promoter.bx.psu.edu/hi-c/) based on work of Rao, S. S. P. et al. [13]. The strengths of interaction between different genome regions are positively correlated to the red color (deep red for interaction score > =500, white for interaction score < =0)