Table 2.
Overview of architectures of 8 viral-cellular junctions
| Junction ID | Type | Left element location | Middle element location | Right element location | Overlapping |
|---|---|---|---|---|---|
| S1-2:J-01 | Type 2 | HPV16 E1(211 bp) | NA | chr3:175701251-175701313 (63 bp) NAALADL2 | Left & Right: No overlapping |
| S2-25:J-03 | Type 1 | HPV16 E1(122 bp) | chr9:125080078-125080338(261 bp) SCAI | chr4:148216738-148216850 (159 bp) NR3C2 | Left & Middle: GATGCA Middle & Right: GATC |
| S2-25:J-04 | Type 1 | HPV16 E1(185 bp) | chr17:30708288-30708380(93 bp) | chr1:165472779-165473100(322 bp) | Left &Middle: No overlapping Middle & Right: AGATC |
| C3-64:J-05 | Type 2 | HPV16 E2(325 bp) | NA | chr3:124457727-124457915 (189 bp) KALRN | Left & Right: AA |
| C4-77:J-06 | Type 2 | chr4:185352615-185352687 SNX25(72 bp) | NA | HPV16 L1(310 bp) | Left & Right: No overlapping |
| C5-87:J-07 | Type 2 | chr22:34824077-34824170(93 bp) | NA | HPV16 L1(224 bp) | Left & Right: CAATA |
| C5-87:J-08 | Type 1 | chr22:34819634-3481983 (201 bp) | chrX:109333446-109333511(66 bp) | HPV16 E5 (299 bp) | Left & Middle: GTGG Middle & Right: GTGTT |
| S6-95:J-09 | Type 2 | HPV16 E1(239 bp) | NA | chr16:82782336-82782494 (159 bp) CDH13 | Left & Right: CTGCAA |
Each viral-cellular junction was assigned an unique ID. 8 junctions were divided into 2 types according to the architecture of viral-cellular junctions. Type 1: 3-element junction with the architecture of virus-human-human or human-human-virus. Type 2: 2-element junction with the architecture of virus-human or human-virus. The origin of each elements were shown in column 3, 4 and 5 respectively. The overlapping between every two elements were shown in column 6. NA, not available