TABLE 1.
Scoring Rubric for Biodosimetry Field Phase of Development
Phase | Score | Description |
---|---|---|
Investigative phase | 1 | In vitro/ex vivo radiation model |
2 | Murine in vivo model | |
Early development phase | 3 | NHP in vivo model |
Late development phase | 4A | Human clinical trials |
4B | Human accidental exposure study | |
Deployment ready | 5 | FDA approved |
Notes. This table provides a scoring rubric for phases of development based on deployment readiness according to model type and recent application in documented clinical care of accidental human exposures. As indicated in the text, an additional assessment at each level includes the accessibility of either an automated platform (X) or laboratory surge capacity (Y). An automated platform is comprised of either high-throughput robotics or clinical laboratory processing capability. Laboratory surge capacity represents established networks for work-intensive co-laboratory scoring.