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. Author manuscript; available in PMC: 2017 Feb 8.
Published in final edited form as: Nat Chem. 2016 Aug 8;8(12):1126–1130. doi: 10.1038/nchem.2587

Fig. 4.

Fig. 4

Examination of substrate scope for the Ni-catalysed cross-electrophile coupling. (a) Reaction conditions employed. (b) Results with new amidine ligands compared to dmbpy (C1) and 2,2’:6’,2”-terpyridine. These results demonstrate that the new primary amidine ligands A1, A8, and A15 as well as N-cyanoamidine A11 are generally superior to bipyridine C1. The advantage of A15 for heterocycle coupling reactions is not only due to it being tridentate because terpyridine gives a poor yield. iAssay yield from UPLC (UV-vis) or GC (FID). iiIsolated yield after chromatography or crystallization. ND = no product detected.