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. 2016 Aug 30;3(3):333–346. doi: 10.3233/JND-160150

Table 3.

Neoepitope biomarkers with relevance to neuromuscular disorders covering a spectrum of processes connected to the disease

Type of marker Related to process Application in muscle Refs
C1M, C3M Collagen 1,3 degradation Inflammation in muscle tissue [123]
PINP, C1M Collagen I synthesis, ECM remodeling Fibrosis [84, 103]
CAF Agrin fragmentation Functional disintegration in neuromuscular [82]
junction, sarcopenia
Titin Muscle metabolism Muscle turnover [87, 124]