Table 4.
The fimbrial adhesins of ETEC and their receptors
Fimbriae | Adhesins | Intestinal receptor molecules | References |
---|---|---|---|
F4ab | FaeG(ab) | b: Transferrin N-glycan (74 kDa)a | 159, 619 |
Galactosylceramide, sulfatide, sulf-lactosylceramide, globotriaosylceramidebc: IMPTGP (210–240 kDa)a,b | 162,620, 621 | ||
bcd: Glycoproteins (45–70 kDa)cAminopeptidase N | 137,160, 161 | ||
F4ac | FaeG(ac) | bc: IMPTGP (210–240 kDa)a | 620, 621 |
Galactosylceramidebcd: Glycoproteins (45–70 kDa)cAminopeptidase N | 162,137,160, 161 | ||
F4ad | FaeG(ad) | d: Neutral glycosphyngolipidsa | 622 |
bcd: Glycoproteins (45–70 kDa)2Aminopeptidase N | 137,160, 161 | ||
F41 | Major subunit | Unknown (erythrocytes: glycophorin AM) | 120, 183 |
F5 | FanC | N-GlycolylsialoparaglobosideN-Glycolyl-GM3 | 139, 140, 189, 190 |
F6 | FasG | SulfatideProteins (32–35 kDa) | 142, 143, 165, 195 |
FasA | Ceramide monohexoside(hydroxylated galactosylcerebroside) | ||
F18ac | FedF | Unknown [F18ab: α(1,2)-fucosyl-containing glycoconjugates] | 205, 206 |
F17a | F17-G | Mucins, glycoproteins (170–200 kDa) | 146 |