Table 8.
Structural characteristics of toxins produced by ETEC
| Toxin | # aa | M | Sequence/arrangementa | Structure |
|---|---|---|---|---|
| STa |
|
|||
| Subtype STaH | 19 | 2,000 | N S S N Y C C E L C C N P A C T G C Y | |
| Subtype STaP | 18 | 2,000 | N T F Y C C E L C C N P A C A G C Y | |
| EAST1 | 38 | 4,100 | Not determined | |
| 17-2 strain | MPSTQYIRRPASSYASCIWCTTACASCHGRTTKPSLAT | |||
| 0-42 strain | MPSTQYIRRPASSYASCIWCATACASCHGRTTKPSLAT | |||
| STb | 48 | 5,200 | STQSNKKDLCEHYRQIAKESCKKGFLGVRDGTAGACFGAQIMVAAKGC |
|
| LTI | 85,000 | AB5 |
|
|
| B-subunit | 103 | 11,600 | ||
| A-subunit | 240 | 28,000 | ||
a
Letters in bold and italics indicate the region involved in binding to the receptor. Underlined letters indicate the change observed for EAST1 variants.