Table S5.
PPV and sensitivity of record of AECOPD or nonspecific hospitalization code to identify hospitalizations for AECOPD using different HES definitions as reference standard allowing 60 days after HES record of hospitalization for AECOPD
| HES AECOPD definition | CPRD strategy | PPV (95% CI) | Sensitivity (95% CI) |
|---|---|---|---|
| AECOPD hospitalization code or LRTI code in any position or COPD in the first position in any FCE | AECOPD identified using algorithm | 2.3% (2.3–2.3) | 46.3% (45.8–46.7) |
| Nonspecific hospitalization code | 14.5% (14.4–14.7) | 55.9% (55.4–56.4) | |
| Either specific AECOPD code in any position or COPD code in the first position | AECOPD identified using algorithm | 2.0% (2.0–2.1) | 46.8% (46.3–47.3) |
| Nonspecific hospitalization code | 12.7% (12.5–12.9) | 56.5% (56.0–57.0) | |
| Either specific AECOPD code in the first position in any FCE | AECOPD identified using algorithm | 1.9% (1.9–1.9) | 47.3% (46.8–47.8) |
| Nonspecific hospitalization code | 12.1% (11.9–12.2) | 57.2% (56.6–57.7) |
Abbreviations: CI, confidence interval; COPD, chronic obstructive pulmonary disease; AECOPD, acute exacerbations of COPD; LRTI, lower respiratory tract infection; HES, Hospital Episodes Statistics; FCE, finished consultant episodes; CPRD, Clinical Practice Research Datalink; PPV, positive predictive value.