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. 2016 Nov 21;8:771–782. doi: 10.2147/CLEP.S117867

Table 4.

Validity of HES definitions of AECOPD hospitalization

Discharge summary analysis Full HES sample analysis

HES definition of AECOPD hospitalization Number of discharge summary-confirmed AECOPD hospitalizations identified using strategy (N=40 events in 40 patients from discharge letters) Sensitivity (95% CI) (% of discharge summary-confirmed AECOPD hospitalizations picked up) (N=40 events in 40 patients from discharge letters) Number of potential AECOPD hospitalization events in total sample identified using strategy (full HES sample for all 27,182 COPD patients included in the study)a
Specific AECOPD code or LRTI code in any position or COPD code in the first position in any FCE during spell 35/40 87.5% (72.4%–94.9%) 40,174
Specific AECOPD code or COPD code in any position in any FCE during spell 34/40 85.0% (69.6%–93.3%) 74,590
Specific AECOPD code in any position or LRTI code or COPD code in the first position in any FCE during spell 34/40 85.0% (69.6%–93.3%) 37,966
Specific AECOPD code in any position or COPD code in the first position in any FCE during spell 31/40 77.5% (61.3%–88.2%) 35,793
Specific AECOPD code in any position in any FCE during spell 31/40 77.5% (61.3%–88.2%) 33,933
Specific AECOPD code in the first position in first FCE during spell 26/40 65.0% (48.5%–78.6%) 21,387

Note:

a

These potential events will represent both true and false positives.

Abbreviations: CI, confidence interval; COPD, chronic obstructive pulmonary disease; AECOPD, acute exacerbations of COPD; LRTI, lower respiratory tract infection; HES, Hospital Episodes Statistics; FCE, finished consultant episodes.