Table 4.
Treatment-confirmed tumor response related to dose exposure
| Tumor response | DTS-108 dose exposure (mg/m2)
|
||||
|---|---|---|---|---|---|
| 3–75 | 100–235 | 313 | 416 | Total | |
| Number of patients | 16 | 14 | 6 | 6 | 42 |
| Complete response, n | 0 | 0 | 0 | 0 | 0 |
| Partial response, n | 0 | 0 | 0 | 0 | 0 |
| Stable disease, n | 3 | 1 | 1 | 1 | 6 |
| Unconfirmed, n | 13 | 13 | 5 | 5 | 36 |
Notes: Confirmed tumor response assessed, using the Response Evaluation Criteria in Solid Tumors criteria, version 1.0, at cycle 3 and partial response or complete response must be confirmed at least 4 weeks after the initial finding.