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. Author manuscript; available in PMC: 2017 Dec 14.
Published in final edited form as: Neuroreport. 2016 Dec 14;27(18):1305–1311. doi: 10.1097/WNR.0000000000000691

Figure 2. LRP1 activates c-Jun in human SCs.

Figure 2

(a) Extracts of human and rat SCs were probed by immunoblot analysis to detect the 85-kDa LRP1 light chain. (b) Immunoblot analysis was performed to detect phosphorylated c-Jun (P-c-Jun) and phosphorylated ERK1/2 (P-ERK1/2) in cultured human SCs treated with PEX (100 nM). Cultures were pretreated with RAP (300 nM) or vehicle as indicated. Equal amounts of cellular protein (5 μg) were loaded into each lane and subjected to SDS-PAGE and electrotransferred to nitrocellulose membranes. β-actin and total ERK1/2 were determined as loading controls. Each blot represents at least 2–3 independent experiments.