Characterization of clinically significant mood symptoms reported on Mania Rating Scale (MRS) and Depression Rating Scale (DRS) over the initial 2 years of follow-up. Note: Symptoms measured on MRS are shown on the left side of the graph, while DRS symptoms are on the right. Youth with bipolar and autism spectrum disorders (BD+ASD) had a higher prevalence of distractibility, depressed mood, poor mood reactivity, and social withdrawal. *p < .05, **p < .01.