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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Oct 20;36(12):2412–2420. doi: 10.1161/ATVBAHA.116.308339

Figure 3. Effect of exercise training on NADPH oxidase-mediated ROS production.

Figure 3

ROS were measured before (Pre) and after (Post) eight weeks of aerobic exercise training in lean, overweight/mildly obese (Int), and obese individuals. (A) ROS was measured without superoxide dismutase (−SOD) in the perfusate, indicative of H2O2 produced endogenously. ROS detected with SOD added (+SOD) to the perfusate is indicative of endogenous superoxide in addition to H2O2. (B) NADPH oxidase (NOX) mediated ROS were determined by calculation of the ROS that was inhibited by the NOX inhibitor apocynin (Apo). NOX-independent ROS were calculated as the fraction of ROS not inhibited by Apo. Values are mean±SEM for n = 9–12 subjects in each group. *P<0.05 vs. pre-training.