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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Oct 20;36(12):2412–2420. doi: 10.1161/ATVBAHA.116.308339

Figure 4. Exercise training effects on skeletal muscle microvascular endothelial function.

Figure 4

Microvascular blood flow was assessed before (Pre) and after (Post) eight weeks of aerobic exercise training in lean, overweight/mildly obese (Int), and obese subjects. (A) Basal blood flow. (B) Blood flow with apocynin perfusion. (C) Microvascular endothelial function, assessed by change in blood flow from basal (Δ Blood Flow) in response to acetylcholine perfusion. (D) Effect of NADPH oxidase on microvascular endothelial function, assessed by change in blood flow upon acetylcholine addition to the apocynin perfused probe. (E) Microvascular endothelium-independent blood flow was assessed by change in blood flow from baseline upon addition of sodium nitroprusside (SNP) to the perfusate. Values are mean±SEM for n = 9–12 subjects per group. *P<0.05 vs. pre-training.