Table 3.

Associations between continuous and finely categorized prescribed ultrafiltration rate and all-cause mortality.

	n (%)	HR (95% CI)
		Unadjusted	Adjustedb
Mean UF rate, mL/h/kg	118,394 (100.0%)	1.01 (1.01–1.02)	1.03 (1.02–1.03)
Mean UF rate
<6 mL/h/kg	23,813 (20.1%)	1.00 (reference)	1.00 (reference)
6–<8 mL/h/kg	21,729 (18.4%)	0.99 (0.96–1.02)	1.03 (1.00–1.07)
8–<10 mL/h/kg	24,323 (20.5%)	1.01 (0.98–1.04)	1.09 (1.06–1.12)
10–<12 mL/h/kg	19,457 (16.4%)	1.04 (1.01–1.07)	1.15 (1.12–1.19)
12–<14 mL/h/kg	13,086 (11.1%)	1.08 (1.05–1.12)	1.23 (1.18–1.27)
≥14 mL/h/kg	15,986 (13.5%)	1.19 (1.15–1.23)	1.43 (1.39–1.48)

Note: Fine and Gray proportional subdistribution hazards regression models with kidney transplantation and dialysis modality change treated as competing risks were used to estimate the ultrafiltration rate and all-cause mortality association.

^bAdjusted for baseline age (continuous), sex (female vs. male), race (black vs. non-black), ethnicity (Hispanic vs. non-Hispanic), dialysis vintage (1–2, 3–4, ≥5 vs. <1 year), vascular access (graft, fistula vs. catheter), history of heart failure (yes vs. no), history of cardiovascular disease (yes vs. no), history of diabetes (yes vs. no), albumin (3.1–3.5, 3.6–4.0, >4.0 vs. ≤3.0 g/dL), creatinine (continuous), phosphorous (4.1–5.0, 5.1–6.0, >6.0 vs. ≤ 4.0 mg/dL), hemoglobin (10.0–11.9, ≥12.0 vs. <10.0 g/dL), urea reduction ratio (continuous), pre-hemodialysis systolic blood pressure (131–150, 151–170, >170 vs. ≤130 mmHg), missed sessions (≥3 vs. <3).

Abbreviations: HR=hazard ratio, CI=confidence interval, UF=ultrafiltration.