Table 3.
Predictors of 25-OH Vitamin D and Lipid testing in children exposed to chronic glucocorticoid therapy
| 25-hydroxyvitamin D | Lipid Screening | |||||||
|---|---|---|---|---|---|---|---|---|
| Variable |
Univariate OR
(95% CI) |
p |
Multivariate OR
(95% CI) |
p |
Univariate OR
(95% CI) |
p |
Multivariate OR
(95% CI) |
p |
| Age, years(baseline) | 1.11 (1.07, 1.14) | <0.001 | 1.10 (1.05, 1.14) | <0.001 | 1.03 (1.00, 1.07) | 0.05 | 1.06 (1.01, 1.11) | 0.008 |
| Follow up duration, months |
1.05 (1.03, 1.08) | <0.001 | 1.05 (1.03, 1.08) | <0.001 | 1.05 (1.02, 1.07) | <0.001 | 1.03 (1.00, 1.05) | 0.03 |
| Sex, Male | 0.70 (0.50, 0.98) | 0.04 | 0.55 (0.37, 0.83) | 0.004 | 0.73 (0.53, 1.02) | 0.07 | -- | -- |
| Race, Non-White | 0.81 (0.57, 1.15) | 0.24 | -- | -- | 1.90 (1.35, 2.65) | <0.001 | -- | -- |
| Hispanic Ethnicity | 0.59 (0.34, 1.00) | 0.05 | 0.49 (0.27, 0.92) | 0.03 | 1.63 (0.96, 2.77) | 0.07 | -- | -- |
| Non-Private Insurance | 0.70 (0.48, 1.02) | 0.06 | -- | -- | 1.38 (0.96, 2.01) | 0.09 | -- | -- |
| Height Z-Score, SD (baseline) |
0.83 (0.73, 0.95) | 0.008 | 0.79 (0.67, 0.93) | 0.004 | 0.77 (0.67, 0.87) | <0.001 | 0.70 (0.60, 0.82) | <0.001 |
| BMI Z-Score, SD (baseline) |
0.74 (0.64, 0.86) | <0.001 | 0.83 (0.71, 0.98) | 0.03 | 1.37 (1.19, 1.57) | <0.001 | 1.25 (1.07, 1.47) | 0.006 |
| In Network Care | 0.99 (0.65, 1.49) | 0.96 | 1.57 (1.07, 2.32) | 0.02 | 1.86 (1.17, 2.97) | 0.009 | ||
| GC Cumulative Dose Quartile |
||||||||
| 1 | Reference | -- | -- | Reference | -- | -- | -- | |
| 2 | 1.32 (0.82, 2.13) | 0.26 | -- | -- | 1.28 (0.80, 2.03) | 0.30 | -- | -- |
| 3 | 1.44 (0.89, 2.35) | 0.14 | -- | -- | 1.46 (0.93, 2.32) | 0.10 | -- | -- |
| 4 | 0.77 (0.49, 1.21) | 0.26 | -- | -- | 0.91 (0.57, 1.48) | 0.71 | -- | -- |
| Subspecialty | ||||||||
| Gastroenterology | Reference | Reference | -- | Reference | -- | Reference | -- | |
| Nephrology | 0.39 (0.27, 0.58) | <0.001 | 0.39 (0.25, 0.63) | <0.001 | 6.68 (4.39, 10.16) | <0.001 | 6.85 (4.28, 10.96) | <0.001 |
| Rheumatology | 0.39 (0.25, 0.60) | <0.001 | 0.28 (0.16, 0.46) | <0.001 | 5.58 (3.54, 8.82) | <0.001 | 5.85 (3.52, 9.70) | <0.001 |
Influenza vaccination data are provided only for the 2012-2013 influenza season and for those receiving primary care in the hospital network. The multivariate model for 25OHD included: Age, Follow-Up Time, Sex, Ethnicity, Baseline Height Z-Score, Baseline BMI Z-Score, Specialty. The multivariate model for lipid screening included: Age, Follow-Up Time, Baseline Height Z-Score, Baseline BMI Z-Score, In Network, Specialty