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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: NMR Biomed. 2016 Oct 3;29(12):1678–1687. doi: 10.1002/nbm.3629

Figure 7. CNO increases LFP beta frequency oscillations in mPFC.

Figure 7

Representative raw LFP and pseudocolor LFP sonogram analysis for a CNO-treated rat expressing DREADDs in mPFC. Representative examples of mPFC LFPs before (A) and 15 min after (B) CNO administration. Pseudocolor sonograms show changes in broad band (0–50Hz) oscillatory power after CNO, while top trace shows change in beta frequency oscillations (15–35Hz) relative to baseline (dashed horizontal line). (C) Change in broad band oscillatory power (0–100Hz) 5 min and 15 min after CNO injection relative to pre-injection baseline (n=4 rats). (D) Time course of mean change in beta frequency power from pre-CNO baseline. Increase in beta power is significant (repeated measures ANOVA, F(4,16) = 3.01, p < 0.05).