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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Brain Res. 2016 Oct 19;1654(Pt A):34–42. doi: 10.1016/j.brainres.2016.10.018

Figure 2. SB-334867 attenuates alcohol self-administration behavior in HR, but not LR rats.

Figure 2

(A) In HR animals, SB10 and SB20 treatment significantly reduced active (but not inactive) lever responses during a 2-hr self-administration session. (B) HR animals also showed a significant reduction in the number of rewarded (but not non-rewarded) well entries following SB treatment. (C, D) In contrast to HR rats, self-administration behavior in LR rats was unaffected by SB treatment. *p<0.05; ** p<0.01; *** p<0.001; n.s. not significant.