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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Brain Res. 2016 Oct 19;1654(Pt A):34–42. doi: 10.1016/j.brainres.2016.10.018

Figure 4. SB-334867 attenuates cue-induced reinstatement of alcohol seeking behavior in HR but not LR.

Figure 4

rats. (A) HR animals showed a significant reinstatement of active lever responding during cue-induced reinstatement tests. This reinstatement was blocked by SB20 treatment. (B) Similarly, SB20 significantly attenuated the number of ‘rewarded’ well entries during cue-induced reinstatement tests and also reduced the number of non-rewarded well entries made. (C) SB20 treatment had no effect on the number of active or inactive lever responses made during reinstatement tests. (D) SB20 also did not affect the number of ‘rewarded’ or non-rewarded well entries made during testing. *p<0.05; ** p<0.01.