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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Food Chem Toxicol. 2016 Oct 20;98(Pt B):107–118. doi: 10.1016/j.fct.2016.10.021

Figure 1.

Figure 1

Acetaminophen-induced liver injury in C57BL/6J and C57BL/6N mice. Animals were treated with 200 mg/kg APAP or saline as control. (A) Plasma ALT activities of C57BL/6J and C57BL/6N mice at 0.5, 2, and 8 h. (B) Representative H&E-stained liver section (×50 magnification) and (C) TUNEL staining (×50 magnification) are shown for controls and animals treated with APAP for 2 h and 8 h. Data represent means ± SE of n=4 animals per group. *p< 0.05 (compared with controls, t=0). #p< 0.05 (compared with C57BL/6J mice treated with APAP).