Figure 1. Adjusted associations of blood pressure components with atherosclerotic cardiovascular disease (stroke, myocardial infarction and peripheral arterial disease) among participants with eGFR<30 ml/min/1.73 m2. The smooth spline estimates the hazard ratio of atherosclerotic cardiovascular disease among CRIC participants with eGFR<30 ml/min/1.73 m2 according to (A) systolic blood pressure; (B) diastolic blood pressure and (C) pulse pressure.
All analyses are adjusted for age, gender, race/ethnicity, clinical site, tobacco use, BMI, diabetes, urine proteinuria, statin use, number of BP medication classes and prevalent CVD. Dotted lines represent 95% confidence intervals. Below each spline is the histogram of the distribution of the blood pressure component to indicate the range of the majority of the data.