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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Stem Cells. 2016 Sep 1;34(12):2916–2929. doi: 10.1002/stem.2471

Figure 1.

Figure 1

Sodium butyrate (NaBu) exerts dose-dependent effects on CMC proliferation and histone acetylation. (A): Growth curves corresponding to two independent patient-derived CMC samples exposed to increasing concentrations of NaBu. Relative cell viability was calculated at 24 h intervals over a period of 5 ds (n=3 for each). Values are mean ± SEM. (B): Representative immunoblots (n=2 for each) detecting acetylated nucleosomal histone proteins in cell lysates from CMCs treated with NaBu for 72 h; employed antibodies include anti-AcK (top panel; anti-acetylated lysine), anti-AcK9-H3 (middle panel; anti-acetylated lysine 9 of histone H3), and anti-β-actin (bottom panel).