HDAC1 knockdown augments cardiogenic protein expression in human CMCs. (A): Immunoblots evaluating the expression of cardiogenic-specific proteins (Mef2C; n=5, Gata4; n=5, and Tbx5b; n=4) 72 h after cell transduction with HDAC1, HDAC4, HDAC7, or non-target control (NT) shRNA constructs. (B): Densitometric quantification of accompanying Mef2c (n=5), Gata4 (n=5), or Tbx5 (n=4) immunoblots. Values represent mean protein expression (relative to β-actin) ± SEM. * P <0.05 (Relative to NT shRNA) and † P <0.005 (Relative to NT shRNA).