Table 3.

Treatment Decisions and Subsequent Diagnostic Characteristics for Infections with Organisms Recovered from CSF culture(s) in the Study Cohort (n=115)

First CSF shunt infection
Overall duration of intravenous (IV) antibiotic use (days), median (IQR)	19 (12, 28)
Concordant IV antibiotic use, n (%)	113 (98%)
Duration (days), median (IQR)	16 (11, 24)
Concordant and appropriate IV antibiotic use, n (%)	111 (97%)
Duration (days), median (IQR)	14 (8, 20)
Broad spectrum IV antibiotic use, n (%)	115 (100%)
Duration (days), median (IQR)	5 (3, 14)
Use of IV antibiotics after shunt replacement, n (%)	26 (23%)
Duration (days), median (IQR)	2 (0, 6)
Use of outpatient antibiotics after shunt replacement, n (%)	14 (12%)
Use of intrathecal antibiotics, n (%)	68 (59%)
Use of rifampin, n (%)	30 (26%)
Time from first positive culture to first infection surgery (hours), median (IQR)	8 (0, 19)
Time from first negative culture to final surgical approach to infection (days), median (IQR)	14 (10, 21)
Duration of positive CSF cultures in days, median (IQR)	3 (1, 6)
Intermittent negative CSF cultures, n (%)	18 (16%)
Secondary ventriculitis, n (%)	15 (13%)
Polymicrobial CSF culture, n (%)	15 (13%)
Culture positive from broth only, n (%)	19 (17%)