Table 1.

Physicochemical characterization of rapamycin and paclitaxel/rapamycin-loaded liposomes.

Formulation	Encapsulation Efficiency (%)	Particle Size (nm)	Polydispersity	Zeta potential (mv)
DPPC:RAP (10:1)	40.74 ± 7.45	145.91 ± 1.84	0.26 ± 0.05	−14.30±1.95
DSPC:RAP (10:1)	44,23±5.98	202.65 ± 10.15	0.76 ± 0.05	−14.77 ± 1.06
DOPE:AO:RAP (10:2.5:1)	45.32 ± 3.98	167.10 ± 1.84	1.16 ± 0.01	−48.73 ± 2.14
SPC:RAP (10:1)	88.42 ± 4.92	130.15 ± 1.20	0.32 ± 0.02	−35.96 ± 2.60
SPC:Chol:RAP (10:1:1)	48.42 ± 5.67	158.60 ± 10.93	0.36 ± 0.09	−27.83 ± 1.25
SPC:Chol:RAP (10:2:1)	66.67 ± 6,76	142.15 ± 6.43	0.24 ± 0.04	−27.50 ± 0.78
SPC:Chol :RAP(10:3:1)	62.67 ± 9,34	135.25 ± 10.45	0.41 ± 0.01	−26.23 ± 0.70
SPC:Chol:DSPE-PEG2000:RAP (10:2:0.5:1)	59.58 ± 4.97	133.84 ± 8.35	0.26 ± 0.01	−3.51 ± 0.24