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P2Y2R is expressed in cyst-lining cells in vivo. Representative photos of a human ADPKD kidney and b PKD1 orthologous mouse knockout kidney stained for P2Y2R (red), nuclei (DAPI; blue) and Dolichos biflorus agglutinin (DBA; green) showing expression of P2Y2R in the apical membrane of DBA-positive cysts
