Table 1.

Interactions of drugs employed in OAB with food and recommendations on their administration

Drug	Drug–food interaction	Recommendations
Darifenacin	Potential interaction with grapefruit juice	May be taken irrespectively of a meal Exercise caution while consuming grapefruit juice during therapy
Fesoterodine	Potential interaction with grapefruit juice	May be taken irrespectively of a meal Avoid consumption of grapefruit juice during therapy
Oxybutynin	Potential interaction with grapefruit juice	May be taken irrespectively of a meal In patients manifesting disturbances of saliva secretion during therapy, taking the drug 0.5–1 h prior to a planned meal is recommended Exercise caution while consuming grapefruit juice during therapy
Solifenacin	Potential interaction with grapefruit juice	May be taken irrespectively of a meal Grapefruit juice should not be consumed during solifenacin therapy
Tolterodine	Data unavailable	May be taken irrespectively of a meal
Trospium	Food, especially high in fats, decreases absorption of the drug	To be taken 1 h prior to a meal or on an empty stomach
Mirabegron	Data unavailable	May be taken irrespectively of a meal