Table 2.
Cox univariate and multivariate analyses of prognostic factors for the overall survival of non-metastatic nasopharyngeal carcinoma patients after treatment
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| P value | HR | 95% CI | P value | |
| Sex | 0.023 | 1.228 | 1.093–1.363 | 0.163 |
| Age | <0.001 | 1.572 | 1.478–1.666 | <0.001 |
| Smoking history | 0.025 | 0.957 | 0.845–1.070 | 0.833 |
| Alcohol consumption | 0.048 | 1.056 | 0.930–1.182 | 0.279 |
| BMI | 0.014 | 1.164 | 1.087–1.241 | 0.004 |
| Hemoglobin | 0.079 | Not included in the multivariate analysis | ||
| NLR | <0.001 | 1.324 | 1.225–1.423 | 0.001 |
| Platelet count | 0.015 | 1.165 | 1.048–1.282 | 0.366 |
| LDH level | <0.001 | 1.332 | 1.273–1.391 | <0.001 |
| ALP level | 0.001 | 1.235 | 1.126–1.344 | 0.185 |
| Histological type | 0.032 | 0.986 | 0.538–1.434 | 0.082 |
| T stage | <0.001 | 1.264 | 1.212–1.316 | <0.001 |
| N stage | <0.001 | 1.457 | 1.399–1.515 | <0.001 |
| TNM stage | <0.001 | Excluded due to collinearity | ||
| VCA-IgA titer | 0.099 | Not included in the multivariate analysis | ||
| EA-IgA | 0.001 | 1.224 | 1.100–1.348 | 0.179 |
| Anti-DNase titer | 0.019 | 1.155 | 1.022–1.288 | 0.43 |
| Neoadjuvant chemotherapy | <0.001 | 1.209 | 1.111–1.308 | 0.043 |
| Concomitant chemotherapy | 0.022 | 1.167 | 1.060–1.274 | 0.424 |
| Adjuvant chemotherapy | 0.035 | 1.747 | 1.238–2.256 | 0.37 |
| Radiation dose | 0.002 | 1.415 | 1.282–1.548 | 0.009 |
HR hazard ratio; CI confidence interval. Other abbreviations as in Table 1