Table 2.
The relationship of expression levels of SOX21 and SOX21-AS1 with clinicopathologic data of OSCC patients
| Variables | SOX21 (n = 86) | SOX21-AS1 (n = 86) | ||||
|---|---|---|---|---|---|---|
| Low expression | High expression | P value | Low expression | High expression | P value | |
| Number (%) | Number (%) | Number (%) | Number (%) | |||
| Sex | ||||||
| Female | 5 (55.6) | 4 (44.4) | 1.000a | 2 (22.2) | 7 (77.8) | 0.712a |
| Male | 38 (49.4) | 39 (50.6) | 27 (35.1) | 50 (64.9) | ||
| Age | ||||||
| ≤50 | 12 (54.5) | 10 (45.5) | 0.621b | 8 (36.4) | 14 (63.6) | 0.761b |
| >50 | 31 (48.4) | 33 (51.6) | 21 (32.8) | 43 (67.2) | ||
| Cancer location | ||||||
| Buccal and other oral mucosal sites | 36 (54.5) | 30 (45.5) | 0.126b | 25 (37.9) | 41 (62.1) | 0.138b |
| Tongue | 7 (35.0) | 13 (65.0) | 4 (20.0) | 16 (80.0) | ||
| Cell differentiation | ||||||
| Well | 5 (41.7) | 7 (58.3) | 0.534b | 4 (33.3) | 8 (66.7) | 1.000a |
| Moderate, poor | 38 (51.4) | 36 (48.6) | 25 (33.8) | 49 (66.2) | ||
| AJCC pathological stage | ||||||
| I | 6 (37.5) | 10 (62.5) | 0.268b | 2 (12.5) | 14 (87.5) | 0.047 b |
| II, III, IV | 37 (52.9) | 33 (47.1) | 27 (38.6) | 43 (61.4) | ||
| T classification | ||||||
| T1 | 6 (35.3) | 11 (64.7) | 0.176b | 2 (11.8) | 15 (88.2) | 0.033 b |
| T2, T3, T4 | 37 (53.6) | 32 (46.4) | 27 (39.1) | 42 (60.9) | ||
| N classification | ||||||
| N0 | 32 (50.0) | 32 (50.0) | 1.000b | 20 (31.2) | 44 (68.8) | 0.683b |
| N1, N2 | 11 (50.0) | 11 (50.0) | 9 (40.9) | 13 (59.1) | ||
The italic indicated p value <0.05
a P value was estimated by Fisher’s exact test
b P value was estimated by chi-square test