. 2016 Nov 25;16:164. doi: 10.1186/s12890-016-0319-9

Table 3.

Mortality, mortality rates, mortality rate ratio expressed as score test for trend for a one unit increase in troponin category, by selected covariates

	High-sensitivity troponin, ng/L			MRR (95% CI)
	<5.0	5.0–13.99	≥14
	(n = 95)	(n = 114)	(n = 66)
Covariate	m (MR)	m (MR)	m (MR)	Unadjusted	Adjusted^a
All, crude	9 (2.8)	17 (4.4)	21 (11.0)	2.1 (1.4–3.1)	-
Age at inclusion, years
< 62	2 (1.4)	3 (2.4)	3 (7.0)	2.4 (0.9–6.6)	1.9 (1.3–2.8)
62–66	3 (3.1)	4 (3.2)	5 (7.8)	1.7 (0.8–3.6)
≥ 67	4 (4.6)	10 (7.2)	13 (15.5)	1.9 (1.1–3.1)
Gender
Female	8 (3.7)	9 (4.7)	11 (15.3)	2.2 (1.3–3.8)	2.3 (1.5–3.4)
Male	1 (0.9)	8 (4.1)	10 (8.4)	2.3 (1.2–4.3)	2.3 (1.5–3.4)
Diabetes
Yes	0 (0)	0 (0)	6 (25.7)	2.5 (1.1–5.9)	1.9 (1.3–2.8)
No	9 (2.9)	17 (4.5)	15 (8.9)	1.8 (1.2–2.7)	1.9 (1.3–2.8)
GOLD class
I–II	2 (1.1)	4 (2.2)	4 (9.5)	3.4 (1.3–8.7)	1.8 (1.2–2.6)
III–IV	7 (4.6)	13 (6.4)	17 (11.4)	1.6 (1.1–2.4)	1.8 (1.2–2.6)
PaO2 < 8 kPa
Yes	3 (5.3)	2 (3.2)	7 (19.6)	2.3 (1.1–4.8)	2.1 (1.4–3.0)
No	6 (2.2)	15 (4.6)	14 (9.0)	2.1 (1.4–3.1)	2.1 (1.4–3.0)
Pathologic Q-wave
Yes	1 (7.4)	1 (5.2)	5 (17.9)	1.7 (0.7–4.4)	2.0 (1.4–2.9)
No	8 (2.6)	16 (4.4)	16 (10.3)	2.1 (1.4–3.2)	2.0 (1.4–2.9)
Leucocytes > 7×10⁹/L
Yes	6 (3.6)	12 (6.7)	16 (14.2)	2.0 (1.3–3.1)	2.0 (1.4–2.9)
No	3 (1.9)	5 (2.4)	5 (6.4)	1.9 (0.9–4.2)	2.0 (1.4–2.9)
Heart rate, > 71 per min
Yes	7 (4.8)	11 (5.9)	16 (12.2)	1.7 (1.1–2.6)	1.9 (1.3–2.8)
No	2 (1.1)	6 (3.0)	5 (8.3)	2.9 (1.3–6.4)	1.9 (1.3–2.8)
GFR
< 45 mL/min	0 (0)	1 (12.1)	3 (37.2)	2.8 (0.4–19.8)	1.9 (1.2–3.0)
45–60 mL/min	1 (1.7)	3 (9.3)	4 (11.4)	2.2 (1.0–5.0)
> 60 mL/min	8 (3.0)	9 (3.7)	14 (9.5)	1.9 (1.2–2.9)
6MWD, <450 m
Yes	7 (5.6)	12 (7.8)	16 (12.6)	1.5 (1.0–2.3)	1.7 (1.2–2.5)
No	2 (1.0)	5 (2.1)	5 (7.8)	3.1 (1.4–7.3)	1.7 (1.2–2.5)
mMRC > 2
Yes	6 (4.4)	10 (5.0)	17 (12.6)	1.8 (1.2–2.8)	1.9 (1.3–2.8)
No	3 (1.6)	7 (3.7)	4 (7.1)	2.2 (1.0–4.8)	1.9 (1.3–2.8)

^aMantel Haenzel test