Fig. 2.

Ex-vivo survival after exposure to DHA. Ex-vivo RSA exposed 93 isolates obtained from patients with uncomplicated falciparum malaria to 700 nM DHA or dimethyl sulfoxide (DHA solvent) during 6 h. Data were considered interpretable if the growth rate was ≥1. a Results obtained in the ex vivo RSA from the 64 isolates with interpretable data (growth rate was ≥1) are expressed as the survival rate of P. falciparum parasites after a 6 hour exposure to 700 nM DHA compared with dimethyl sulfoxide (DHA solvent). The horizontal line represents the mean and whiskers the interquartile range. b Survival rates obtained in the ex vivo RSA from the 64 isolates with interpretable data are expressed in the two groups, day 2 PNR and day 2 PPR. Day 2 PNR represented the proportion of non-parasitaemic patients on day 2 whereas day PPR 2 represented the proportion of patients remaining parasitaemic on day 2, respectively. The ex vivo RSA data were analysed using the t-test for two group comparisons