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. 2016 Nov 26;15:572. doi: 10.1186/s12936-016-1622-x

Table 2.

Clinical and parasitological characteristics at day 2

Day 2 (n = 64) P value
PPR PNR
n (%) 8 (12.5%) 56 (87.5%)
Age (years)
Median (IQR)
7.5 (5–14.3) 12 (6–22) 0.236a
 <8 years
n (%)
4 (50%) 19 (33.9%) 0.893b
 8–15 years
n (%)
2 (25%) 15 (26.8%)
 >15 years
n (%)
2 (25%) 22 (39.3%)
Weight (kg)
Median (IQR)
26 (18–58.3) 39 (21–61) 0.551a
P. falciparum density (parasites/µl)
Day 0
Median (IQR)
81,260 (35,110–133,200) 44,260 (17,720–87,300) 0.150a
Day 2
Median (IQR)
293 (145–736) 0
Parasite decrease rate (%)
Median (IQR)
99.6 (98.9–99.8) 100
Symptoms n (%)
 Headache 0 (0%) 3 (5.3%) 1.000c
 Vomiting 0 (0%) 1 (1.8%) 1.000c
 Diarrhoea 0 (0%) 0 (0%) 1.000c
 Diffuse pain 0 (0%) 0 (0%) 1.000c
 Fever (≥38 °C) 0 (0%) 1 (1.8%) 1.000c
Anti-malarial dose (mg/kg)
DHA
 Median (IQR) 2.4 (1.9–3.1) 2.4 (2.0–2.9) 0.570a
 <25 kg 2.5 (2.4–3.4) 2.8 (2.4–3.4) 0.891a
 ≥25 kg 2.3 (1.8–3.1) 2.1 (1.8–2.6) 0.425a
PPQ
 Median (IQR) 19.4 (15.5–24.6) 18.8 (15.7–22.9) 0.570a
 <25 kg 20.0 (18.8–03.5) 22.1 (18.8–27.5) 0.891a
 ≥25 kg 18.3 (14.1–24.6) 17.1 (14.3–20.4) 0.425a

Day 2 PPR: proportion of patients remaining parasitaemic on day 2

Day 2 PNR: proportion of patients without parasitaemia on day 2

aMann–Whitney U test

bChi2 test

cFisher’s exact test