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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Gastroenterology. 2016 Aug 26;151(6):1164–1175.e3. doi: 10.1053/j.gastro.2016.08.014

Figure 7. Recombination in cagY modulates T4SS function during chronic infection in humans.

Figure 7

(A) cagY PCR-RFLP analysis of sequential A and B H pylori isolates. Arrowheads denote bands that changed in isolate A and B, which were collected from the same patient 7.4 years apart. (B) IL8 induction normalized to strain PMSS1 for sequential H pylori isolates A and B, their cagY knockouts (Δ), and strains in which their cagY genes have been exchanged. ***P≤0.001,****P≤0.0001.