Table 2.
Demographic and clinical features by treatment response of patients who were compliant with the lid hygiene routine (n=104)
| Demographics | No improvement | Partial improvement | Complete improvement | P-value |
|---|---|---|---|---|
| Age, mean (SD) [n] | 69 (4) [8] | 69 (11) [30] | 68 (11) [66] | 0.86 |
| Gender, male % (n) | 8% (8) | 28% (27) | 64% (61) | 0.64 |
| female % (n) | 0% (0) | 37.5% (3) | 62.5% (5) | |
| Race, white % (n) | 7% (5) | 31% (21) | 62% (42) | 0.82 |
| black % (n) | 8% (3) | 25% (9) | 67% (24) | |
| Ethnicity, non-Hispanic % (n) | 2 (10% ) | 24% (5) | 67% (14) | 0.82 |
| Hispanic % (n) | 6 (7%) | 30% (25) | 63% (52) | |
| Co-Morbidities | ||||
| Glaucoma, Yes % (n) | 12% (4) | 27% (9) | 61% (20) | 0.51 |
| No % (n) | 6% (4) | 30% (21) | 65% (46) | |
| DEQ5 score, mean (SD) [n] | 8.0 (7.5) [8] | 6.7 (4.9) [30] | 6.7 (4.9) [66] | 0.78 |
| DEQ5≥12, Yes % (n) | 13% (3) | 26% (6) | 61% (14) | 0.55 |
| No % (n) | 6% (5) | 30% (24) | 64% (52) | |
| Duration of symptoms (in those with symptoms) mean (SD) [n] | 7.8 (9.8) [5] | 5.8 (7.0) [28] | 2.7 (3.6) [53] | 0.02 |
| Rosacea, Yes % (n) | 4.5% (2) | 36% (16) | 59% (26) | 0.26 |
| No % (n) | 10% (6) | 23% (14) | 67% (40) | |
| Medications | ||||
| Artificial tears, Yes % (n) | 7% (4) | 37% (22) | 57% (34) | 0.14 |
| No % (n) | 9% (4) | 19% (8) | 72% (31) | |
| Glaucoma medications, Yes % (n) | 16% (4) | 20% (5) | 64% (16) | 0.15 |
| No % (n) | 5% (4) | 32% (25) | 63% (50) | |
| Prostaglandin analogs, Yes % (n) | 14% (3) | 23% (5) | 64% (14) | 0.44 |
| No % (n) | 6% (5) | 31% (5) | 63% (52) | |
| Eyelid and corneal findings | ||||
| Anterior blepharitis, mean (SD) [n] | 0.63 (0.52) [8] | 0.83 (0.87) [30] | 0.71 (0.80) [66] | 0.73 |
| Anterior blepharitis≥2, Yes % (n) | 0% (0) | 37% (7) | 63% (12) | 0.32 |
| No % (n) | 9% (8) | 27% (23) | 64% (54) | |
| Eyelid vascularity, mean (SD) [n] | 0.75 (0.89) [8] | 1.23 (1.04) [30] | 0.88 (0.98) [66] | 0.22 |
| Eyelid vascularity≥2, Yes % (n) | 7% (2) | 33% (10) | 60% (18) | 0.81 |
| No % (n) | 8% (6) | 27% (20) | 65% (48) | |
| Inspissation, mean (SD) [n] | 1.75 (1.04) [8] | 1.33 (1.06) [30] | 1.11 (0.86) [66] | 0.14 |
| Inspissation≥2, Yes % (n) | 8% (3) | 31% (11) | 61% (22) | 0.94 |
| No % (n) | 7% (5) | 28% (19) | 65% (44) | |
| Meibum quality, mean (SD) [n] | 1.63 (1.51) [8] | 2.07 (1.41) [30] | 1.58 (1.33) [66] | 0.26 |
| Meibum quality≥2, Yes % (n) | 4% (2) | 33% (17) | 64% (33) | 0.28 |
| No % (n) | 11.5% (6) | 25% (13) | 63.5% (33) | |
| Corneal staining, mean (SD) [n] | 1.50 (1.31) [8] | 1.13 (1.17) [30] | 1.29 (1.36) [66] | 0.75 |
| Corneal staining≥2, Yes % (n) | 5% (2) | 30% (11) | 65% (24) | 0.81 |
| No % (n) | 9% (6) | 28% (19) | 63% (42) |
SD=standard deviation; n=number in group