Supplementary Table 1.

Down-regulated lactation-related miRNAs (E-value <6.00E-04).

Original species	miRNA	Human genome homologous	Conservation	E-value	Number of target genes
Cow	mir-181d-5p	hsa-miR-181d-5p	1	2.00E-04	222
Cow	mir-574-3p	hsa-miR-574-3p	1	6.00E-04	6
Cow	mir-107-3p	hsa-miR-107	1	6.00E-04	53
Cow	bta-let-7c	hsa-let-7c-5p	1	6.00E-04	64
Cow	mir-10a-5p	hsa-miR-10a-5p	1	6.00E-04	19
Cow	mir-100-5p	hsa-miR-100-5p	1	6.00E-04	4
Cow	mir-199a-3p	hsa-miR-199a-3p	1	6.00E-04	39
Cow	mir-221-3p	hsa-miR-221-3p	1	6.00E-04	36
Cow	mir-205-5p	hsa-miR-205-5p	1	6.00E-04	43
Cow	mir-146b-5p	hsa-miR-146b-5p	1	6.00E-04	13
Cow	mir-327-5p	hsa-miR-221-5p	1	6.00E-04	36
Cow	mir-199b-5p	hsa-miR-199b-5p	1	6.00E-04	39
Cow	mir-203-3p	hsa-miR-203a-3p	1	6.00E-04	94
Cow	mir-26-1-5p	hsa-miR-26a-5p	0.98	6.00E-04	118
Cow	mir-181c-5p	hsa-miR-181c-5p	0.99	6.00E-04	151
Rat	rno-miR-134-5p	hsa-miR-134-5p	1	6.00E-04	8
Rat	rno-miR-23a-5p	hsa-miR-23a-5p	1	6.00E-04	103
Rat	rno-miR-27a-5p	hsa-miR-27a-5p	1	6.00E-04	118