Table 2.
Biochemical plasma analysis (mean ± SEM), according to group: control; mild colitis; lipoic acid, LA; N-acetylcysteine, NAC; LA associated with NAC – LA + NAC.
| Control | Mild colitis | LA | NAC | LA + NAC | |
|---|---|---|---|---|---|
| Hb1Ac (%)Ψ | 7.80 ± 0.15 | 7.97 ± 0.29 | 8.50 ± 0.40 | 8.13 ± 0.33 | 7.88 ± 0.28 |
| Glucose (mg/dL) | 189.00 ± 31.35 | 207.80 ± 38.77 | 196.00 ± 61.01 | 156.2 ± 23.66 | 176.40 ± 18.76 |
| CRP (mg/dL) | 2.22 ± 0.32 | 2.20 ± 0.16 | 1.90 ± 0.25 | 2.15 ± 0.30 | 2.18 ± 0.29 |
| Calcium (mg/dL) | 9.25 ± 0.31 | 8.90 ± 0.29 | 8.13 ± 0.90 | 8.68 ± 0.23 | 8.64 ± 0.41 |
| TC (mg/dL) | 76.00 ± 7.69 | 65.75 ± 7.20 | 70.50 ± 5.50 | 72.25 ± 5.45 | 64.33 ± 8.67 |
| TG (mg/dL) | 55.50 ± 14.56 | 63.25 ± 14.48 | 53.50 ± 0.71 | 54.25 ± 7.01 | 50.20 ± 19.83 |
| LDL-C (mg/dL) | 37.56 ± 14.37 | 30.32 ± 5.67 | 31.80 ± 3.60 | 35.90 ± 5.37 | 29.96 ± 5.70 |
| HDL-C (mg/dL) | 27.33 ± 2.26 | 24.50 ± 1.76 | 28.00 ± 2.00 | 25.50 ± 0.87 | 23.60 ± 3.17 |
| AST (U/L) | 167.50 ± 27.91 | 194.00 ± 20.72 | 297.75 ± 59.74 | 153.40 ± 20.34 | 359.75 ± 76.95αδ |
| ALT (U/L) | 82.83 ± 5.83 | 104.25 ± 6.14 | 133.00 ± 24.78 | 85.25 ± 6.02 | 168.25 ± 38.60αδ |
| AP (U/L) | 420.50 ± 33.84 | 345.00 ± 12.45 | 315.00 ± 66.24 | 302.40 ± 46.64 | 305.00 ± 53.97 |
| TB (mg/dL) | 0.12 ± 0.00 | 0.10 ± 0.02 | 0.10 ± 0.02 | 0.12 ± 0.01 | 0.10 ± 0.02 |
| DB (mg/dL)Ψ | 0.03 ± 0.00 | 0.02 ± 0.00 | 0.03 ± 0.00 | 0.02 ± 0.00 | 0.03 ± 0.00 |
| IB (mg/dL)Ψ | 0.10 ± 0.00 | 0.07 ± 0.02 | 0.08 ± 0.00 | 0.09 ± 0.01 | 0.08 ± 0.01 |
| TP (g/dL) | 5.24 ± 0.19 | 4.63 ± 0.48 | 4.20 ± 0.41 | 4.78 ± 0.17 | 4.66 ± 0.14 |
| ALB (g/dL) | 2.90 ± 0.27 | 2.28 ± 0.89 | 2.50 ± 0.46 | 2.74 ± 0.18 | 2.68 ± 0.15 |
| GLOB (g/dL) | 2.30 ± 0.09 | 1.95 ± 0.03 | 1.70 ± 0.15αα | 2.04 ± 0.10 | 1.98 ± 0.10 |
Hb1Ac = glycosylated hemoglobin; CRP = C reactive protein; TC = total cholesterol; TG = triacylglycerol; LDL-C = low-density lipoprotein; HDL-C = high density lipoprotein; AST = aspartate aminotransferase; ALT = alanine aminotransferase; AP = alkaline phosphatase; TB = total bilirubin; DB = direct bilirubin; IB = indirect bilirubin; TP = total protein; ALB = albumin; GLOB = globulin; α p < 0.05 versus control; αα p < 0.01 versus control; δ p < 0.05 versus NAC (Tukey test). ΨKruskal-Wallis and Dunn's test.