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Oxymatrine induces apoptosis of GBM cells. (a, c) U251 and A172 cells treated for 24 hours with DMSO and indicated concentrations of OMT or TMZ. Expression of caspase-3, Bax, and Bcl-2 was analysed by Western blot. (b, d) Expression analyses were normalized to that of the negative control group (fold versus CON). ∗ P < 0.05, ∗∗ P < 0.01, and ∗∗∗ P < 0.001.
