Table 3.

Multivariable cox proportional hazards model for OS and CSS.

	HR OS (95% CI)		HR CSS (95% CI)
Age	1.04 (1.04–1.05)	p<0.001	1.03 (1.02–1.04)	p<0.001
Sex
- Male	N/A		Reference
- Female			1.05 (0.87–1.26)	p=0.6
Tumor size	1.003 (1.002–1.005)	p<0.001	1.004 (1.001–1.01)	p=0.003
Tumor Grade
- Grade 1	Reference		Reference
- Grade 2	1.43 (0.93–2.20)	p=0.1	2.53 (0.91–6.07)	p=0.054
- Grade 3	2.01 (1.33–3.03)	p=0.001	5.12 (2.03–12.49)	p<0.001
- Grade 4	2.26 (1.51–3.40)	p<0.001	5.74 (2.32–14.18)	p<0.001
- Unknown	2.01 (1.22–3.32)	p=0.006	5.13 (2.11–15.46)	p=0.001
pT stage
- T1	Reference		Reference
- T2	1.44 (1.17–1.77)	p=0.001	1.64 (1.17–2.24)	p=0.003
- T3	2.20 (1.85–2.63)	p<0.001	3.08 (2.37–4.09)	p<0.001
- T4	4.13 (3.19–5.34)	p<0.001	6.16 (4.37–9.21)	p<0.001
- Unknown	3.88 (0.95–15.87)	p=0.06	7.82 (1.09–60.34)	p=0.04
pN stage
- N0	Reference		Reference
- N1	2.01 (1.48–2.72)	p<0.001	2.33 (1.50–3.28)	p<0.001
- N2/3	1.94 (1.34–2.81)	p<0.001	1.83 (1.04–3.15)	p=0.01
- Nx	1.12 (0.91–1.39)	p=0.3	0.97 (0.78–1.42)	p=0.8
pM stage
- M0	Reference		Reference
- M1	3.20 (2.42–4.23)	p<0.001	3.64 (2.59–5.12)	p<0.001
- Mx	1.90 (1.16–3.13)	p=0.01	2.53 (1.39–4.61)	p=0.002
Tumor location
- Renal Pelvis	Reference		Reference
- Ureter	1.18 (1.03–1.35)	p=0.02	1.29 (1.07–1.56)	p=0.008
Number of Nodes Removed	0.99 (0.97–1.02)	p=0.5	0.94 (0.91–0.98)	p=0.003