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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Am J Obstet Gynecol. 2016 Jul 22;215(6):795.e1–795.e14. doi: 10.1016/j.ajog.2016.07.039

Table 4. Mixed effects spline regression models (risk ratio with 95% confidence interval) for severe morbidity and failure to rescue.

Severe Morbidity Model Failure to Rescue model
Annualized delivery volume See figure 1-a See figure 1-b
Age
 <20 0.98 (0.96-0.99) 0.81 (0.67-0.99)
 20-24 1.00 (Referent)
 25-29 1.14 (1.13-1.16) 1.15 (1.02-1.29))
 30-34 1.32 (1.30-1.33) 1.34 (1.19-1.52)
 ≥35 0.89 (0.88-0.90) 1.75 (1.55-1.98)
Year
 1998 1.00 (Referent) 1.00 (Referent)
 1999 1.05 (1.02-1.07) 1.36 (1.06-1.73)
 2000 1.02 (0.99-1.05) 1.16 (0.89-1.50)
 2001 1.06 (1.04-1.09) 1.07 (0.82-1.40)
 2002 1.11 (1.08-1.14) 1.09 (0.85-1.40)
 2003 1.11 (1.08-1.14) 0.91 (0.71-1.18)
 2004 1.13 (1.10-1.16) 0.79 (0.61-1.01)
 2005 1.11 (1.08-1.14) 0.93 (0.72-1.20)
 2006 1.19 (1.16-1.22) 0.58 (0.44-0.76)
 2007 1.14 (1.12-1.17) 0.57 (0.43-0.74)
 2008 1.33 (1.29-1.36) 0.73 (0.56-0.94)
 2009 1.32 (1.29-1.36) 0.81 (0.63-1.05)
 2010 1.28 (1.25-1.32) 0.81 (0.63-1.05)
Household income
 Lowest quartile 1.00 (Referent) 1.00 (Referent)
 Second quartile 1.02 (1.01-1.03) 1.21 (1.08-1.36)
 Third quartile 1.00 (0.99-1.01) 0.93 (0.81-1.06)
 Highest quartile 0.96 (0.95-0.97) 0.89 (0.77-1.04)
 Unknown 1.02 (0.99-1.05) 1.08 (0.79-1.47)
Insurance status
 Medicare 1.62 (1.56-1.68) 1.20 (0.83-1.72)
 Medicaid 1.17 (1.16-1.18) 1.34 (1.21-1.47)
 Private 1.00 (Referent) 1.00 (Referent)
 Self pay 1.09 (1.07-1.12) 1.43 (1.17-1.73)
 Other 1.20 (1.17-1.22) 1.48 (1.19-1.85)
 Unknown 1.22 (1.13-1.32) 0.78 (0.31-1.96)
Race
 White 1.00 (Referent) 1.00 (Referent)
 Black 1.19 (1.18-1.21) 1.77 (1.56-2.00)
 Hispanic 0.90 (0.88-0.91) 1.34 (1.17-1.54)
 Other/unknown 1.15 (1.13-1.16) 1.10 (0.96-1.27)
Hospital bed size
 Small (<400) 1.00 (Referent) 1.00 (Referent)
 Medium (400-600) 1.03 (1.00-1.07) 1.25 (0.89-1.76)
 Large (>600) 1.14 (1.10-1.18) 1.66 (1.15-2.39)
Hospital Location
 Rural 1.00 (Referent) 1.00 (Referent)
 Urban 1.08 (1.03-1.13) 1.11 (0.65-1.90)
Hospital Region
 Northeast 1.00 (Referent) 1.00 (Referent)
 Midwest 0.88 (0.80-0.96) 0.79 (0.37-1.72)
 South 1.23 (1.12-1.35) 2.18 (1.03-4.58)
 West 1.01 (0.91-1.11) 2.19 (1.01-4.77)
Hospital Teaching
 Non-teaching 1.00 (Referent) 1.00 (Referent)
 Teaching 0.96 (0.92-0.99) 0.99 (0.67-1.46)
 Unknown 0.90 (0.86-0.95) 2.18 (1.40-3.39)
Hospital Owner
 Government 1.00 (Referent)
 Private non-profit 1.03 (0.98-1.08) 1.00 (Referent) 0.58 (0.34-0.98)
 Private investor 0.95 (0.89-1.01) 0.71 (0.39-1.31)
 Unknown/other 1.17 (1.11-1.24) 1.11 (0.60-2.04)
Comorbidity Index 1.56 (1.56-1.56) 1.07 (1.05-1.09)

For severe morbidity, annualized delivery volume was modeled based on a 5-piece restricted cubic spline transformation with knot locations at 377, 1252, 2170, 3437, and 7163. For failure to rescue annualized delivery volume was modeled based on a 5-piece restricted cubic spline transformation with knot locations at 432, 1478, 2378, 3600, and 7433.