Table 2.
Association between PFTs, pulmonary symptoms, and ILD among patients with abnormal PFTs and CT available for review
| No ILD (n = 24) |
ILD (n = 15) |
p-valuea | |
|---|---|---|---|
| PFT pattern | |||
| Isolated low DLCO | 11 (46%) | 5 (44%) | 0.52 |
| Restriction | 6 (25%) | 6 (40%) | 0.48 |
| Obstruction | 4 (17%) | 0 (0%) | 0.15 |
| Mixed | 0 (0%) | 2 (13%) | 0.14 |
| Indeterminate | 3 (12%) | 2 (13%) | 1.0 |
| DLCO % predicted | 70 [64, 78] | 62 [54, 70] | 0.06 |
| FVC % predicted | 81 [76, 96] | 76 [68, 86] | 0.08 |
| TLC % predicted | 90 [74, 99] | 77 [72, 84] | 0.02 |
| Dyspnea | 8 (33%) | 10 (67%) | 0.06 |
| Cough | 5 (21%) | 5 (33%) | 0.46 |
| Neither | 14 (58%) | 5 (33%) | 0.19 |
Median [IQR] compared with Wilcoxon rank-sum, Number (%) compared with Fisher’s exact test.
a
No p-values met statistical significance after Bonferroni correction for multiple comparisons.
PFT: pulmonary function tests, CT: computed tomography scan of the chest, ILD: interstitial lung disease, DLCO: diffusion capacity for carbon monoxide, FVC: forced vital capacity, TLC: total lung capacity