Table 5.
Variables Considered as Candidates in Multiple Variable Modeling
| Variable | HR (95% CI) | P-value | Global P- value |
|---|---|---|---|
| Age at trauma, per 10 years | 1.2 (1.1, 1.3) | <0.001 | |
| Male sex | 1.4 (0.99, 1.9) | 0.057 | |
| Body mass index | 0.006 | ||
| Normal | 1.0 (ref) | ||
| Overweight | 1.7 (1.2, 2.5) | 0.003 | |
| Obese | 1.7 (1.1, 2.6) | 0.025 | |
| Current or past tobacco smoker | 1.6 (1.1, 2.2) | 0.006 | |
| Trauma Mortality Prediction Model (TMPM), per 10 % increase |
1.6 (1.4, 1.8) | <0.001 | |
| Any blood product transfusion | 0.9 (0.6, 1.3) | 0.509 | |
| Any non-hospital related immobility prior to trauma | 1.7 (1.2, 2.6) | 0.005 | |
| Days from trauma to hospital admission | 0.055 | ||
| 0 (day of admission) | 1.0 (ref) | ||
| 1–2 | 0.6 (0.4, 0.98) | 0.043 | |
| >2 | 1.2 (0.7, 1.8) | 0.486 | |
| Hospitalized within 3 months prior to trauma | 1.1 (0.7, 1.7) | 0.682 | |
| Additional hospitalization after trauma admission | 1.5 (1.0, 2.1) | 0.035 | |
| Congestive heart failure | 1.7 (1.1, 2.5) | 0.013 | |
| Hyperlipidemia | 1.4 (0.98, 2.0) | 0.067 | |
| Chronic lung disease | 1.3 (0.8, 1.9) | 0.279 | |
| Hormone therapy | 1.3 (0.6, 2.7) | 0.555 | |
| Prior superficial vein thrombosis | 3.1 (1.8, 5.2) | <0.001 | |
| Blunt Injury | 0.6 (0.4, 1.00) | 0.05 | |
| Pelvic fracture | 1.6 (0.9, 3.0) | 0.116 | |
| Spinal fracture | 1.5 (0.9,2.5) | 0.134 | |
| Leg fracture | 0.7 (0.5, 0.97) | 0.032 | |
| Arm fracture | 0.6 (0.4, 1.1) | 0.129 | |
| Soft tissue injury, leg | 1.9 (1.2, 2.9) | 0.003 | |
| Soft tissue injury, arm | 1.2 (0.7, 2.0) | 0.458 | |
| Active cancer | 2.5 (1.4, 4.3) | 0.002 | |
| Number of surgeries after trauma | 0.002 | ||
| 0 | 1.0 (ref) | ||
| 1 | 0.7 (0.5, 1.1) | 0.114 | |
| >1 | 2.3 (1.3, 4.2) | 0.006 | |
| Mechanical prophylaxis | 1.6 (0.9, 2.8) | 0.082 | |
| Chemoprophylaxis | 0.9 (0.5, 1.5) | 0.600 | |