Table 4.

Analyses of covariance comparing log SBP values of untreated (not taking antihypertensive medications) PWH and NHANES subjects after adjusting for age and each covariate.

Covariate	Regression coefficient for Z (PWH versus NHANES)			r 2
	b	95% CI	P
Young adults (18–29 years)
No covariates (age  +  Z only)	0.069	0.050, 0.088	<0.001	0.085
log BMI	0.073	0.058, 0.088	<0.001	0.177
log (1 + Creatinine)	0.068	0.052, 0.084	<0.001	0.110
eGFR	0.068	0.052, 0.084	<0.001	0.110
log TotalCholesterol	0.079	0.060, 0.098	<0.001	0.094
Smoking status	0.071	0.052, 0.089	<0.001	0.087
HCV	0.066	0.048, 0.085	<0.001	0.104
Race	0.068	0.053, 0.083	<0.001	0.101
All covariates∗	0.081	0.057, 0.105	<0.001	0.159
Older adults (30–79 years)
No covariates (age  +  Z only)	0.031	0.013, 0.049	<0.001	0.041
log BMI	0.046	0.030, 0.061	<0.001	0.087
log (1 + Creatinine)	0.038	0.022, 0.054	<0.001	0.052
eGFR	0.037	0.020, 0.053	<0.001	0.052
log TotalCholesterol	0.036	0.017, 0.056	<0.001	0.060
Smoking status	0.035	0.017, 0.052	<0.001	0.043
HCV	0.012	−0.015, 0.039	0.384	0.051
Race	0.038	0.022, 0.053	<0.001	0.055
All covariates∗	0.005	−0.027, 0.036	0.769	0.121
All covariates except HCV	0.049	0.029, 0.069	<0.001	0.111

Z indicates the binary variable that distinguishes PWH from NHANES (Z = 1 for PWH, Z = 0 for NHANES); PWH, patients with hemophilia; NHANES, subjects from the National Health and Nutrition Examination Survey of the general United States population; b, regression coefficient for Z representing change in log SBP per unit increase of the selected covariate; CI, confidence interval; r ², square of the multiple correlation coefficient; BMI, body mass index; eGFR, estimated glomerular filtration rate; HCV, hepatitis C virus.

^∗Age, log BMI, eGFR, log TotalCholesterol, smoking status, HCV, and race.