Table 7.
Analyses of covariance comparing DBP values of treated (taking antihypertensive medications) PWH and NHANES subjects after adjusting for age and each covariate.
| Covariate | Regression coefficient for Z (PWH versus NHANES) | r 2 | ||
|---|---|---|---|---|
| b | 95% CI | P | ||
| Older adults (30–79 years) | ||||
| No covariates (Cage + Cage 2 + Z only) | 6.40 | 3.75, 9.05 | <0.001 | 0.165 |
| log BMI | 6.13 | 3.79, 8.47 | <0.001 | 0.175 |
| log (1 + Creatinine) | 6.92 | 4.62, 9.21 | <0.001 | 0.168 |
| eGFR | 6.73 | 4.45, 9.00 | <0.001 | 0.172 |
| log TotalCholesterol | 8.53 | 5.97, 11.10 | <0.001 | 0.224 |
| Diabetes | 6.60 | 4.34, 8.85 | <0.001 | 0.179 |
| Smoking status | 6.57 | 3.95, 9.19 | <0.001 | 0.164 |
| HCV | 6.97 | 3.13, 18.81 | <0.001 | 0.170 |
| Race | 6.68 | 4.42, 8.95 | <0.001 | 0.175 |
| All covariates∗ | 6.68 | 2.26, 11.10 | 0.003 | 0.239 |
Z indicates the binary variable that distinguishes PWH from NHANES (Z = 1 for PWH, Z = 0 for NHANES); PWH, patients with hemophilia; NHANES, subjects from the National Health and Nutrition Examination Survey of the general United States population; b, regression coefficient for Z representing change in log SBP per unit increase of the selected covariate; CI, confidence interval; r 2, square of the multiple correlation coefficient; BMI, body mass index; eGFR, estimated glomerular filtration rate; HCV, hepatitis C virus.
∗ Cage, Cage 2, log BMI, eGFR, log TotalCholesterol, diabetes, smoking status, HCV, and race.