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. 2016 Feb 4;33(23):2125–2132. doi: 10.1089/neu.2015.4320

Table 1.

Results of Weighted Zero-Inflated Negative Binomial Regression Evaluating Effects of Sex, Pre-Deployment General Distress, Pre-Deployment Traumatic Brain Injury History, Deployment Stress Severity, and Deployment-Acquired Traumatic Brain Injury* on Presence (Yes/No; Adjusted Odds Ratio) and Severity (for Nonzero Scores; Fold Change) of Post-Deployment Post-Concussive Symptoms in Soldiers With and Without Mild Traumatic Brain Injury (n = 4518)

  3 months post-deployment (T2) 9 months post-deployment (T3)
  AORa 95% CI p FCb 95% CI p AORa 95% CI p FCb 95% CI p
Female sex 1.34 0.50–3.58 0.551 1.19 1.07–1.33 0.002 1.46 0.91–2.32 0.110 1.23 1.10–1.37 0.001
Pre-deployment past-month general distress 1.39 1.11–1.73 0.005 1.01 1.01–1.01 <0.001 1.14 1.06–1.22 0.001 1.01 1.01–1.01 <0.001
Deployment stress severity 1.09 1.00–1.19 0.050 1.05 1.04–1.06 <0.001 1.10 1.04–1.16 0.001 1.04 1.03–1.05 <0.001
Any lifetime pre-deployment TBI with LOC 1.34 0.91–1.98 0.133 1.10 1.05–1.15 <0.001 1.59 1.19–2.11 0.002 1.10 1.03–1.17 0.004
Any deployment-acquired mild TBI 2.88 1.64–5.05 <0.001 1.31 1.24–1.39 <0.001 2.92 1.82–4.68 <0.001 1.23 1.16–1.31 <0.001

AOR, adjusted odds ratio; CI, confidence interval; FC, fold change. Post-concussive symptoms (PCS) were measured with the PCS-8, which assessed severity of: balance problems or dizziness, sensitivity to noise, sensitivity to light, memory problems, irritability, difficulty concentrating, headaches, and feeling tired out or being easily fatigued.

*

Models also adjust for age group (<30 years vs. older), race, ethnicity, brigade combat team, and number of previous deployments.

a

For ease of interpretation, AORs reported in the table indicate odds of a nonzero score on the PCS-8 (i.e., presence of any symptoms) that are associated with each hypothesized predictor. These AORs were calculated by taking the inverse of the AORs for odds of a zero score (not shown in Table).

b

FCs indicate the fold increase or decrease in PCS-8 score associated with each predictor when any symptoms are present (i.e., when PCS-8 score is nonzero).