. 2016 Dec 1;33(23):2133–2146. doi: 10.1089/neu.2015.4267

Table 1C.

Associations Between HITS Metrics and Changes in DKI-Derived Metrics in White Matter (± SD 2.0)

	Without covariate adjustment		Covariate adjustment for age, BMI, and time between scans
	R²	p value	Adjusted R²	Covariate-adjusted R²	p value
MK vs. RWE_CP	0.1411	0.0705	0.4993	0.4807	0.0015^*
K axial vs. RWE_CP	0.1891	0.0337^*	0.5735	0.5597	0.0004^*
K radial vs. RWE_CP	0.1474	0.0640	0.4024	0.4194	0.0071^*
MK vs. RWE_Linear	0.0347	0.3837	0.2699	0.2427	0.0391^*
K axial vs. RWE_Linear	0.0398	0.3497	0.3342	0.3126	0.0180^*
K radial vs. RWE_Linear	0.0443	0.3233	0.3438	0.2283	0.0779
MK vs. RWE_Rotational	0.0769	0.1894	0.1604	0.1291	0.1210
K axial vs. RWE_Rotational	0.0004	0.9252	0.0642	0.0339	0.2736
K radial vs. RWE_Rotational	0.0612	0.2438	0.0713	0.0977	0.2590
MK vs. total impacts	0.0073	0.6923	0.0739	0.0394	0.2539
K axial vs. total impacts	0.0006	0.9134	0.0714	0.0413	0.2588
K radial vs. total impacts	0.0128	0.5984	0.0253	0.0530	0.3640
MK vs. summed linear acceleration	0.0104	0.6360	0.1036	0.1116	0.1996
K axial vs. summed linear acceleration	0.0001	0.0029	0.1084	0.1670	0.1917
K radial vs. summed linear acceleration	0.0170	0.3798	0.0554	0.1288	0.2926
MK vs. summed rotational acceleration	0.0129	0.5972	0.1072	0.1143	0.1937
K axial vs. summed rotational acceleration	0.0005	0.9178	0.1085	0.1630	0.1916
K radial vs. summed rotational acceleration	0.0197	0.5129	0.0572	0.1279	0.2886

^{^*}

p < 0.05. Bold p values.

HITS, Head Impact Telemetry System; DKI, diffusional kurtosis imaging; SD, standard deviation; BMI, body mass index; MK, mean kurtosis; RWEcp, Risk Weighted Cumulative Exposure combined probability; K axial, axial kurtosis; K radial, radial kurtosis.