FIG. 1.

Zebrafish larval xenograft. (A–A₂) Schematic representation of the xenograft technique, lateral view. (A) Zebrafish larvae were mounted in low-melting point agarose (beige). (A₁) Larval heads were released from the low-melting point agarose to allow cell transplantation into the brain. (A₂) Cells (red) were transplanted into the optic tectum. (B–B₃) Schematic representation of the xenograft technique, dorsal view. Cells (red) were transplanted into the left optic tectum, stimulating a microglia (green) response (depending on cell type). The right optic tectum served as an internal control.