Table 2.
Variables of receiver-operating characteristic (ROC) analysis for the three parameters analyzed either alone or in combination for the differential diagnosis of benign and malignant tumours
| Variables | ADC | FA | SWV | Combination |
|---|---|---|---|---|
| AUC | 0.69 | 0.76 | 0.91 | 0.92 |
| Cut-off point | 1.02 (10−3 mm2 s−1) | 0.24 | 2.76 (m s−1) | 0 |
| Sensitivity (with 95% CI) | 87.50 | 62.50 | 68.75 | 87.50 |
| Specificity % (with 95% CI) | 45.71 | 82.86 | 97.14 | 97.14 |
| p-value (Z-test) | 0.01 | 0.002 | <0.0001 | <0.0001 |
| Youden index (J) | 0.33 | 0.45 | 0.66 | 0.85 |
ADC, apparent diffusion coefficient; AUC, area under the ROC curve; CI, confidence interval; FA, fractional anisotropy; SWV, shear-wave velocity.
For combination analysis, parallel test was conducted first to obtain the combination, followed by ROC analyses to acquire all variables.