Table 4.
Diffusion tensor imaging analyses on the left centrum semiovale: comparison between patients with Cockayne syndrome (CS) and controls
| DTI parameter | Group of patients with CS | Control group | p-value |
|---|---|---|---|
| FA | 204 ± 40 | 351 ± 50 | p < 0.001 Percentage decrease FA: 58% |
| ADC | 1179.2 ± 139.86 | 853.38 ± 93.50 | p < 0.001 Percentage increase ADC: 38% |
| λ1 | 1432.76 ± 149.63 | 1167.48 ± 83.23 | p < 0.001 Percentage increase λ1: 12% |
| λ2 | 1144.78 ± 160.56 | 832.34 ± 132.27 | p < 0.001 Percentage increase λ2: 37% |
| λ3 | 960.27 ± 138.63 | 560.34 ± 94.83 | p < 0.001 Percentage increase λ3: 71% |
| λt | 1052.53 ± 144.77 | 696.34 ± 103.11 | p < 0.001 Percentage increase λt: 51% |
ADC, apparent diffusion coefficient; FA, fractional anisotropy.
Values are expressed as mean ± standard deviation. FA values (×10−3); ADC, λ1, λ2, λ3, λt values (×10−6 mm2 s−1). p-value <0.05 was considered significant.