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. 2016 Nov 28;6:37589. doi: 10.1038/srep37589

Figure 4. SCFAs regulate beige adipocyte differentiation and mitochondrial biogenesis.

Figure 4

Three- to four-week-old C57BL/6 J male mice were fed different diets for 16 weeks, the mice were sacrificed and the epididymal fat was dissected for measuring mRNA expressions of related genes. (A–F) Mitochondrial biogenesis-related genes (PGC-1a, NRF-1, Tfam, β-F1-ATPase, COX IV and cyt-c); G: mtDNA quantity; (H–J) beige adipocyte markers (Tbx1, Tmem26, CD137). (K–M) correlation between fat GRP43 and related genes. n = 8–10 in each group. *Compared to the lean control (C) group, P < 0.05; #compared to the HFD group, P < 0.05.